New Rh Antibody

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منابع مشابه

Survival after transfusion of Rh-positive erythrocytes previously incubated with Rh antibody.

It has been concluded that if blood is taken from a patient with acquired haemolytic anaemia and transfused to a normal recipient the erythrocytes survive normally (Loutit and Mollison, 1946). This finding is not an easy one to understand since the erythrocytes at the moment of transfusion are coated with antibody and give a positive direct Coombs test, and it might be thought that if the degre...

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Antibody produced against isolated Rh(D) polypeptide reacts with other Rh-related antigens.

Rh(D) antigen-containing polypeptide was prepared by immune precipitation of intact cDE/cDE erythrocytes by using a high-titer preparation of polyclonal anti-D. when isolated Rh(D) polypeptide was administered to rabbits, antibody was produced that was unresponsive toward Rh-positive and -negative cells but reacted strongly with the immunogen in enzyme-linked immunosorbent assay-type immunobind...

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Antibody protein levels in maternal sera in Rh haemolytic disease.

constituent of foetal serum, but it virtually disappears from the circulation very soon after birth and is not detectable in normal adults. The only conditions where cx1FP has been found in the sera of adult humans in significant quantities are primary hepatocellular cancer of the liver and teratocarcinomas. It has been shown that the demonstration of x1FP in the serum of adult patients can be ...

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Human monoclonal antibody against Rh(D) antigen: partial characterization of the Rh(D) polypeptide from human erythrocytes.

A human monoclonal anti-Rh(D) antibody produced by an Epstein-Barr virus (EBV)-transformed B-cell line (IgG1(lambda), clone H2D5D2) has been purified on protein A-Sepharose column and used for binding studies and immune precipitation of the blood group rhesus (Rh) antigens. Scatchard plot analyses show that the 125I-labeled antibody (iodo-gen procedure), binds to 1.09 X 10(5), 0.43 X 10(5), and...

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Observations on the new Rh agglutinin anti-f.

antibodies found in the serum of a hemophiliac who had received numerous blood transfusions. In addition to anti-N, anti-S, and anti-K, the serum contained an antibody which reacted with bloods of certain Rh types, only blood cells from persons bearing at least one chromosome of type cde or cDe being agglutinated by this antibody. It svas postulated that these reactions were due to a new antige...

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ژورنال

عنوان ژورنال: BMJ

سال: 1953

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.1.4824.1390-b